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Spatial statistical tools for genome-wide mutation cluster detection under a microarray probe sampling system

Mutation cluster analysis is critical for understanding certain mutational mechanisms relevant to genetic disease, diversity, and evolution. Yet, whole genome sequencing for detection of mutation clusters is prohibitive with high cost for most organisms and population surveys. Single nucleotide poly...

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Detalles Bibliográficos
Autores principales: Luo, Bin, Edge, Alanna K., Tolg, Cornelia, Turley, Eva A., Dean, C. B., Hill, Kathleen A., Kulperger, R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155535/
https://www.ncbi.nlm.nih.gov/pubmed/30252889
http://dx.doi.org/10.1371/journal.pone.0204156