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Dexamethasone counteracts hepatic inflammation and oxidative stress in cholestatic rats via CAR activation

Glucocorticoids (GCs) are currently used for the therapeutic management of cholestatic diseases, but their use and molecular mechanism remain controversial. The aims of this study were 1) to assess the therapeutic effect of a 2-week treatment with the GC dexamethasone on hepatic damage in bile duct-...

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Detalles Bibliográficos
Autores principales: Gabbia, Daniela, Pozzo, Luisa, Zigiotto, Giorgia, Roverso, Marco, Sacchi, Diana, Dalla Pozza, Arianna, Carrara, Maria, Bogialli, Sara, Floreani, Annarosa, Guido, Maria, De Martin, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155538/
https://www.ncbi.nlm.nih.gov/pubmed/30252871
http://dx.doi.org/10.1371/journal.pone.0204336