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Dexamethasone counteracts hepatic inflammation and oxidative stress in cholestatic rats via CAR activation
Glucocorticoids (GCs) are currently used for the therapeutic management of cholestatic diseases, but their use and molecular mechanism remain controversial. The aims of this study were 1) to assess the therapeutic effect of a 2-week treatment with the GC dexamethasone on hepatic damage in bile duct-...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155538/ https://www.ncbi.nlm.nih.gov/pubmed/30252871 http://dx.doi.org/10.1371/journal.pone.0204336 |