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Colonic levels of vasoactive intestinal peptide decrease during infection and exogenous VIP protects epithelial mitochondria against the negative effects of IFNγ and TNFα induced during Citrobacter rodentium infection

Citrobacter rodentium infection is a model for infection with attaching and effacing pathogens, such as enteropathogenic Escherichia coli. The vasoactive intestinal peptide (VIP) has emerged as an anti-inflammatory agent, documented to inhibit Th1 immune responses and successfully treat animal model...

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Detalles Bibliográficos
Autores principales: Maiti, Arpan K., Sharba, Sinan, Navabi, Nazanin, Lindén, Sara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155558/
https://www.ncbi.nlm.nih.gov/pubmed/30252907
http://dx.doi.org/10.1371/journal.pone.0204567