Substitution at the C-3 Position of Catechins Has an Influence on the Binding Affinities against Serum Albumin

It is known that catechins interact with the tryptophan (Trp) residue at the drug-binding site of serum albumin. In this study, we used catechin derivatives to investigate which position of the catechin structure strongly influences the binding affinity against bovine serum albumin (BSA) and human s...

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Detalles Bibliográficos
Autores principales: Ikeda, Masaki, Ueda-Wakagi, Manabu, Hayashibara, Kaori, Kitano, Rei, Kawase, Masaya, Kaihatsu, Kunihiro, Kato, Nobuo, Suhara, Yoshitomo, Osakabe, Naomi, Ashida, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155608/
https://www.ncbi.nlm.nih.gov/pubmed/28218710
http://dx.doi.org/10.3390/molecules22020314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155608/
https://www.ncbi.nlm.nih.gov/pubmed/28218710
http://dx.doi.org/10.3390/molecules22020314

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