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Fenofibrate Therapy Restores Antioxidant Protection and Improves Myocardial Insulin Resistance in a Rat Model of Metabolic Syndrome and Myocardial Ischemia: The Role of Angiotensin II

Renin-angiotensin system (RAS) activation promotes oxidative stress which increases the risk of cardiac dysfunction in metabolic syndrome (MetS) and favors local insulin resistance. Fibrates regulate RAS improving MetS, type-2 diabetes and cardiovascular diseases. We studied the effect of fenofibrat...

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Detalles Bibliográficos
Autores principales: Ibarra-Lara, Luz, Sánchez-Aguilar, María, Sánchez-Mendoza, Alicia, Del Valle-Mondragón, Leonardo, Soria-Castro, Elizabeth, Carreón-Torres, Elizabeth, Díaz-Díaz, Eulises, Vázquez-Meza, Héctor, Guarner-Lans, Verónica, Rubio-Ruiz, María Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155612/
https://www.ncbi.nlm.nih.gov/pubmed/28036029
http://dx.doi.org/10.3390/molecules22010031