Synthesis and Biological Evaluation of Novel 8-Morpholinoimidazo[1,2-a]pyrazine Derivatives Bearing Phenylpyridine/Phenylpyrimidine-Carboxamides

Herein we designed and synthesized three series of novel 8-morpholinoimidazo[1,2-a]pyrazine derivatives bearing phenylpyridine/phenylpyrimidine-carboxamides (compounds 12a–g, 13a–g and 14a–g). All the compounds were evaluated for their IC(50) values against three cancer cell lines (A549, PC-3 and MC...

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Detalles Bibliográficos
Autores principales: Xu, Shan, Sun, Chengyu, Chen, Chen, Zheng, Pengwu, Zhou, Yong, Zhou, Hongying, Zhu, Wufu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155691/
https://www.ncbi.nlm.nih.gov/pubmed/28218676
http://dx.doi.org/10.3390/molecules22020310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155691/
https://www.ncbi.nlm.nih.gov/pubmed/28218676
http://dx.doi.org/10.3390/molecules22020310

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