Design, Synthesis and Evaluation of Naphthalimide Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma

Two kinds of naphthalimide derivatives were synthesized and evaluated for in vitro their anti-hepatocellular carcinoma properties. Compound 3a with a fused thiazole fragment to naphthalimide skeleton inhibited cell migration of SMMC-7721 and HepG2, and further in vivo trials with two animal models c...

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Detalles Bibliográficos
Autores principales: Ge, Chaochao, Chang, Liping, Zhao, Ying, Chang, Congcong, Xu, Xiaojuan, He, Haoying, Wang, Yuxia, Dai, Fujun, Xie, Songqiang, Wang, Chaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155709/
https://www.ncbi.nlm.nih.gov/pubmed/28241441
http://dx.doi.org/10.3390/molecules22020342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155709/
https://www.ncbi.nlm.nih.gov/pubmed/28241441
http://dx.doi.org/10.3390/molecules22020342

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