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Design, Synthesis and Evaluation of Naphthalimide Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma
Two kinds of naphthalimide derivatives were synthesized and evaluated for in vitro their anti-hepatocellular carcinoma properties. Compound 3a with a fused thiazole fragment to naphthalimide skeleton inhibited cell migration of SMMC-7721 and HepG2, and further in vivo trials with two animal models c...
Autores principales: | Ge, Chaochao, Chang, Liping, Zhao, Ying, Chang, Congcong, Xu, Xiaojuan, He, Haoying, Wang, Yuxia, Dai, Fujun, Xie, Songqiang, Wang, Chaojie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155709/ https://www.ncbi.nlm.nih.gov/pubmed/28241441 http://dx.doi.org/10.3390/molecules22020342 |
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