Towards Precision Engineering of Canonical Polyketide Synthase Domains: Recent Advances and Future Prospects

Modular polyketide synthases (mPKSs) build functionalized polymeric chains, some of which have become blockbuster therapeutics. Organized into repeating clusters (modules) of independently-folding domains, these assembly-line-like megasynthases can be engineered by introducing non-native components....

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Detalles Bibliográficos
Autores principales: Bayly, Carmen L., Yadav, Vikramaditya G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155766/
https://www.ncbi.nlm.nih.gov/pubmed/28165430
http://dx.doi.org/10.3390/molecules22020235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155766/
https://www.ncbi.nlm.nih.gov/pubmed/28165430
http://dx.doi.org/10.3390/molecules22020235

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