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The Influence of Chitosan Cross-linking on the Properties of Alginate Microparticles with Metformin Hydrochloride—In Vitro and In Vivo Evaluation

Sodium alginate is a polymer with unique ability to gel with different cross-linking agents in result of ionic and electrostatic interactions. Chitosan cross-linked alginate provides improvement of swelling and mucoadhesive properties and might be used to design sustained release dosage forms. There...

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Detalles Bibliográficos
Autores principales: Szekalska, Marta, Sosnowska, Katarzyna, Zakrzeska, Agnieszka, Kasacka, Irena, Lewandowska, Alicja, Winnicka, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155789/
https://www.ncbi.nlm.nih.gov/pubmed/28117747
http://dx.doi.org/10.3390/molecules22010182