A Novel Convergent Synthesis of the Potent Antiglaucoma Agent Tafluprost

Tafluprost (AFP-168, 5) is a unique 15-deoxy-15,15-difluoro-16-phenoxy prostaglandin F(2)α (PGF(2α)) analog used as an efficacious ocular hypotensive agent in the treatment of glaucoma and ocular hypertension, as monotherapy, or as adjunctive therapy to β-blockers. A novel convergent synthesis of 5...

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Detalles Bibliográficos
Autores principales: Krupa, Małgorzata, Chodyński, Michał, Ostaszewska, Anna, Cmoch, Piotr, Dams, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155834/
https://www.ncbi.nlm.nih.gov/pubmed/28146132
http://dx.doi.org/10.3390/molecules22020217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155834/
https://www.ncbi.nlm.nih.gov/pubmed/28146132
http://dx.doi.org/10.3390/molecules22020217

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