Design, Synthesis, and Biological Evaluation of a New Series of Biphenyl/Bibenzyl Derivatives Functioning as Dual Inhibitors of Acetylcholinesterase and Butyrylcholinesterase

Alzheimer’s disease (AD), the most common form of dementia in adults, is a progressive neurodegenerative disorder of the brain characterized by loss of memory and steady deterioration of cognition. Here, a series of symmetrical molecules containing biphenyl/bibenzyl scaffolds (12–36) were designed,...

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Detalles Bibliográficos
Autores principales: Wang, Dong-mei, Feng, Bo, Fu, Hui, Liu, Ai-lin, Wang, Lin, Du, Guan-hua, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155837/
https://www.ncbi.nlm.nih.gov/pubmed/28117700
http://dx.doi.org/10.3390/molecules22010172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155837/
https://www.ncbi.nlm.nih.gov/pubmed/28117700
http://dx.doi.org/10.3390/molecules22010172

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