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Design, Synthesis, and Biological Evaluation of a New Series of Biphenyl/Bibenzyl Derivatives Functioning as Dual Inhibitors of Acetylcholinesterase and Butyrylcholinesterase

Alzheimer’s disease (AD), the most common form of dementia in adults, is a progressive neurodegenerative disorder of the brain characterized by loss of memory and steady deterioration of cognition. Here, a series of symmetrical molecules containing biphenyl/bibenzyl scaffolds (12–36) were designed,...

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Detalles Bibliográficos
Autores principales:	Wang, Dong-mei, Feng, Bo, Fu, Hui, Liu, Ai-lin, Wang, Lin, Du, Guan-hua, Wu, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155837/ https://www.ncbi.nlm.nih.gov/pubmed/28117700 http://dx.doi.org/10.3390/molecules22010172

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