Altholactone Inhibits NF-κB and STAT3 Activation and Induces Reactive Oxygen Species-Mediated Apoptosis in Prostate Cancer DU145 Cells

Altholactone, a natural compound isolated from Goniothalamus spp., has demonstrated anti-inflammatory and anticancer activities, but its molecular mechanisms are still not fully defined. Nuclear factor kappa B (NF-κB) and signal transducer and activator of transcription 3 (STAT3) play pivotal roles...

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Detalles Bibliográficos
Autores principales: Jiang, Chunwa, Masood, Muqaddas, Rasul, Azhar, Wei, Wei, Wang, Ya, Ali, Muhammad, Mustaqeem, Muhammad, Li, Jiang, Li, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155856/
https://www.ncbi.nlm.nih.gov/pubmed/28178219
http://dx.doi.org/10.3390/molecules22020240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155856/
https://www.ncbi.nlm.nih.gov/pubmed/28178219
http://dx.doi.org/10.3390/molecules22020240

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