Asymmetric Total Syntheses of Two 3-Acyl-5,6-dihydro-2H-pyrones: (R)-Podoblastin-S and (R)-Lachnelluloic Acid with Verification of the Absolute Configuration of (−)-Lachnelluloic Acid

Expedient asymmetric total syntheses of both (R)-podoblastin-S and (R)-lachnelluloic acid, representative of natural 3-acyl-5,6-dihydro-2H-pyran-2-ones, were performed. Compared with the reported total synthesis of (R)-podoblastin-S (14 steps, overall 5% yield), the present study was achieved in onl...

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Detalles Bibliográficos
Autores principales: Fujiwara, Tetsuya, Tsutsumi, Takeshi, Nakata, Kohei, Nakatsuji, Hidefumi, Tanabe, Yoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155883/
https://www.ncbi.nlm.nih.gov/pubmed/28045445
http://dx.doi.org/10.3390/molecules22010069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155883/
https://www.ncbi.nlm.nih.gov/pubmed/28045445
http://dx.doi.org/10.3390/molecules22010069

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