Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor

The glucagon-like peptide-1 receptor (GLP-1R) is an important target in the treatment of type 2 diabetes mellitus. The aim of this study was to compare the rate of agonist stimulated desensitization and internalization of GLP-1R. To this end, an N-terminally myc-tagged GLP-1R was stably expressed in...

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Detalles Bibliográficos
Autores principales: Shaaban, Ghina, Oriowo, Mabayoje, Al-Sabah, Suleiman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155907/
https://www.ncbi.nlm.nih.gov/pubmed/28035964
http://dx.doi.org/10.3390/molecules22010022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155907/
https://www.ncbi.nlm.nih.gov/pubmed/28035964
http://dx.doi.org/10.3390/molecules22010022

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