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Synthesis and Antitumor Activities of Chiral Dipeptide Thioureas Containing an Alpha-Aminophosphonate Moiety

Thiourea derivatives demonstrate potent cytotoxic activity against various leukemias and many tumor cell lines. In our previous study, the combination of thiourea and phosphonate has been proven as an effective strategy for developing antitumor agents. Herein, we synthesized and evaluated a series o...

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Detalles Bibliográficos
Autores principales: Liu, Jingzi, Liao, Peng, Hu, Junfeng, Zhu, Hong, Wang, Yonglin, Li, Yongjun, Li, Yan, He, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155911/
https://www.ncbi.nlm.nih.gov/pubmed/28212338
http://dx.doi.org/10.3390/molecules22020238