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Cearoin Induces Autophagy, ERK Activation and Apoptosis via ROS Generation in SH-SY5Y Neuroblastoma Cells

Neuroblastomas are the most common solid extracranial tumors in childhood. We investigated the anticancer effect of cearoin isolated from Dalbergia odorifera in human neuroblastoma SH-SY5Y cells. SH-SY5Y cells were treated with various doses of cearoin. The viability was measured by MTT assay. DCFDA...

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Detalles Bibliográficos
Autores principales: Bastola, Tonking, An, Ren-bo, Kim, Youn-Chul, Kim, Jaehyo, Seo, Jungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155915/
https://www.ncbi.nlm.nih.gov/pubmed/28178193
http://dx.doi.org/10.3390/molecules22020242