Development and Structural Modification of BACE1 Inhibitors

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder which usually occurs in the elderly. The accumulation of β-amyloid and the formation of neurofibrillary tangles are considered as the main pathogenies of AD. Research suggests that β-secretase 1 (BACE1) plays an important role in t...

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Detalles Bibliográficos
Autores principales: Gu, Ting, Wu, Wen-Yu, Dong, Ze-Xi, Yu, Shao-Peng, Sun, Ying, Zhong, Yue, Lu, Yu-Ting, Li, Nian-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155942/
https://www.ncbi.nlm.nih.gov/pubmed/28025519
http://dx.doi.org/10.3390/molecules22010004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155942/
https://www.ncbi.nlm.nih.gov/pubmed/28025519
http://dx.doi.org/10.3390/molecules22010004

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