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Development and Structural Modification of BACE1 Inhibitors

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder which usually occurs in the elderly. The accumulation of β-amyloid and the formation of neurofibrillary tangles are considered as the main pathogenies of AD. Research suggests that β-secretase 1 (BACE1) plays an important role in t...

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Detalles Bibliográficos
Autores principales:	Gu, Ting, Wu, Wen-Yu, Dong, Ze-Xi, Yu, Shao-Peng, Sun, Ying, Zhong, Yue, Lu, Yu-Ting, Li, Nian-Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155942/ https://www.ncbi.nlm.nih.gov/pubmed/28025519 http://dx.doi.org/10.3390/molecules22010004

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