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GADD45a Regulates Olaquindox-Induced DNA Damage and S-Phase Arrest in Human Hepatoma G2 Cells via JNK/p38 Pathways

Olaquindox, a quinoxaline 1,4-dioxide derivative, is widely used as a feed additive in many countries. The potential genotoxicity of olaquindox, hence, is of concern. However, the proper mechanism of toxicity was unclear. The aim of the present study was to investigate the effect of growth arrest an...

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Detalles Bibliográficos
Autores principales: Li, Daowen, Dai, Chongshan, Yang, Xiayun, Li, Bin, Xiao, Xilong, Tang, Shusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155949/
https://www.ncbi.nlm.nih.gov/pubmed/28098804
http://dx.doi.org/10.3390/molecules22010124