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The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8(+) Memory T Cells
During acute lymphocytic choriomeningitis virus infection, pathogen-specific CD8(+) cytotoxic T lymphocytes undergo clonal expansion leading to viral clearance. Following this, the majority of pathogen-specific CD8(+) T cells undergo apoptosis, leaving a small number of memory CD8(+) T cells that pe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156005/ https://www.ncbi.nlm.nih.gov/pubmed/30264035 http://dx.doi.org/10.4049/immunohorizons.1800046 |