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The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8(+) Memory T Cells

During acute lymphocytic choriomeningitis virus infection, pathogen-specific CD8(+) cytotoxic T lymphocytes undergo clonal expansion leading to viral clearance. Following this, the majority of pathogen-specific CD8(+) T cells undergo apoptosis, leaving a small number of memory CD8(+) T cells that pe...

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Detalles Bibliográficos
Autores principales:	Olesin, Elizabeth, Nayar, Ribhu, Saikumar-Lakshmi, Priya, Berg, Leslie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156005/ https://www.ncbi.nlm.nih.gov/pubmed/30264035 http://dx.doi.org/10.4049/immunohorizons.1800046

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