Chemistry and Hypoglycemic Activity of GPR119 Agonist ZB-16

This article is to highlight the chemical properties and primary pharmacology of novel GPR119 agonist ZB-16 and its analogs, which were rejected during the screening. Experiments were performed in vitro (specific activity, metabolism and cell toxicity) and in vivo (hypoglycemic activity and pharmaco...

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Detalles Bibliográficos
Autores principales: Tyurenkov, Ivan N., Kurkin, Denis V., Bakulin, Dmitry A., Volotova, Elena V., Morkovin, Evgeny I., Chafeev, Mikhail A., Karapetian, Ruben N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156125/
https://www.ncbi.nlm.nih.gov/pubmed/30283402
http://dx.doi.org/10.3389/fendo.2018.00543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156125/
https://www.ncbi.nlm.nih.gov/pubmed/30283402
http://dx.doi.org/10.3389/fendo.2018.00543

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