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A Mitochondria-Associated Oxidative Stress Perspective on Huntington’s Disease
Huntington’s disease (HD) is genetically caused by mutation of the Huntingtin (HTT) gene. At present, the mechanisms underlying the defect of HTT and the development of HD remain largely unclear. However, increasing evidence shows the presence of enhanced oxidative stress in HD patients. In this rev...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156126/ https://www.ncbi.nlm.nih.gov/pubmed/30283298 http://dx.doi.org/10.3389/fnmol.2018.00329 |