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A Mitochondria-Associated Oxidative Stress Perspective on Huntington’s Disease

Huntington’s disease (HD) is genetically caused by mutation of the Huntingtin (HTT) gene. At present, the mechanisms underlying the defect of HTT and the development of HD remain largely unclear. However, increasing evidence shows the presence of enhanced oxidative stress in HD patients. In this rev...

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Detalles Bibliográficos
Autores principales: Zheng, Ju, Winderickx, Joris, Franssens, Vanessa, Liu, Beidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156126/
https://www.ncbi.nlm.nih.gov/pubmed/30283298
http://dx.doi.org/10.3389/fnmol.2018.00329

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