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Comprehensively Profiling the Chromatin Architecture of Tissue Restricted Antigen Expression in Thymic Epithelial Cells Over Development

Thymic epithelial cells (TEC) effect crucial roles in thymopoiesis including the control of negative thymocyte selection. This process depends on their capacity to express promiscuously genes encoding tissue-restricted antigens. This competence is accomplished in medullary TEC (mTEC) in part by the...

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Detalles Bibliográficos
Autores principales: Handel, Adam E., Shikama-Dorn, Noriko, Zhanybekova, Saule, Maio, Stefano, Graedel, Annina N., Zuklys, Saulius, Ponting, Chris P., Holländer, Georg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156148/
https://www.ncbi.nlm.nih.gov/pubmed/30283453
http://dx.doi.org/10.3389/fimmu.2018.02120