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The Actin Cytoskeleton: A Mechanical Intermediate for Signal Integration at the Immunological Synapse

The immunological synapse (IS) is a specialized structure that serves as a platform for cell-cell communication between a T cell and an antigen-presenting cell (APC). Engagement of the T cell receptor (TCR) with cognate peptide-MHC complexes on the APC activates the T cell and instructs its differen...

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Detalles Bibliográficos
Autores principales: Roy, Nathan H., Burkhardt, Janis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156151/
https://www.ncbi.nlm.nih.gov/pubmed/30283780
http://dx.doi.org/10.3389/fcell.2018.00116