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The Actin Cytoskeleton: A Mechanical Intermediate for Signal Integration at the Immunological Synapse
The immunological synapse (IS) is a specialized structure that serves as a platform for cell-cell communication between a T cell and an antigen-presenting cell (APC). Engagement of the T cell receptor (TCR) with cognate peptide-MHC complexes on the APC activates the T cell and instructs its differen...
Autores principales: | Roy, Nathan H., Burkhardt, Janis K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156151/ https://www.ncbi.nlm.nih.gov/pubmed/30283780 http://dx.doi.org/10.3389/fcell.2018.00116 |
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