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Antagonistic Pleiotropy in the Bifunctional Surface Protein FadL (OmpP1) during Adaptation of Haemophilus influenzae to Chronic Lung Infection Associated with Chronic Obstructive Pulmonary Disease
Tracking bacterial evolution during chronic infection provides insights into how host selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen nontypeable Haemophilus influenzae (NTHi) infects the lower airways of patients suffering chronic obstructive pulmonary disea...
Autores principales: | Moleres, Javier, Fernández-Calvet, Ariadna, Ehrlich, Rachel L., Martí, Sara, Pérez-Regidor, Lucía, Euba, Begoña, Rodríguez-Arce, Irene, Balashov, Sergey, Cuevas, Ester, Liñares, Josefina, Ardanuy, Carmen, Martín-Santamaría, Sonsoles, Ehrlich, Garth D., Mell, Joshua Chang, Garmendia, Junkal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156194/ https://www.ncbi.nlm.nih.gov/pubmed/30254117 http://dx.doi.org/10.1128/mBio.01176-18 |
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