Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer’s disease mouse model

Alzheimer's disease (AD) is an intractable progressive neurodegenerative disease characterized by cognitive decline and dementia. An inflammatory neurodegenerative pathway, involving Caspase-1 activation, is associated with human age-dependent cognitive impairment and several classical AD brain...

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Detalles Bibliográficos
Autores principales: Flores, Joseph, Noël, Anastasia, Foveau, Bénédicte, Lynham, Jeffrey, Lecrux, Clotilde, LeBlanc, Andréa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156230/
https://www.ncbi.nlm.nih.gov/pubmed/30254377
http://dx.doi.org/10.1038/s41467-018-06449-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156230/
https://www.ncbi.nlm.nih.gov/pubmed/30254377
http://dx.doi.org/10.1038/s41467-018-06449-x

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