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Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders

Histones are positively charged nuclear proteins that facilitate packaging of DNA into nucleosomes common to all eukaryotic cells. Upon cell injury or cell signalling processes, histones are released passively through cell necrosis or actively from immune cells as part of extracellular traps. Extrac...

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Detalles Bibliográficos
Autores principales: Szatmary, Peter, Huang, Wei, Criddle, David, Tepikin, Alexei, Sutton, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156248/
https://www.ncbi.nlm.nih.gov/pubmed/30085397
http://dx.doi.org/10.1111/jcmm.13797