Altered modulation of lamin A/C‐HDAC2 interaction and p21 expression during oxidative stress response in HGPS

Defects in stress response are main determinants of cellular senescence and organism aging. In fibroblasts from patients affected by Hutchinson–Gilford progeria, a severe LMNA‐linked syndrome associated with bone resorption, cardiovascular disorders, and premature aging, we found altered modulation...

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Detalles Bibliográficos
Autores principales: Mattioli, Elisabetta, Andrenacci, Davide, Garofalo, Cecilia, Prencipe, Sabino, Scotlandi, Katia, Remondini, Daniel, Gentilini, Davide, Di Blasio, Anna Maria, Valente, Sergio, Scarano, Emanuela, Cicchilitti, Lucia, Piaggio, Giulia, Mai, Antonello, Lattanzi, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291/
https://www.ncbi.nlm.nih.gov/pubmed/30109767
http://dx.doi.org/10.1111/acel.12824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291/
https://www.ncbi.nlm.nih.gov/pubmed/30109767
http://dx.doi.org/10.1111/acel.12824

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