Monoamine oxidase‐A is a novel driver of stress‐induced premature senescence through inhibition of parkin‐mediated mitophagy

Cellular senescence, the irreversible cell cycle arrest observed in somatic cells, is an important driver of age‐associated diseases. Mitochondria have been implicated in the process of senescence, primarily because they are both sources and targets of reactive oxygen species (ROS). In the heart, ox...

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Detalles Bibliográficos
Autores principales: Manzella, Nicola, Santin, Yohan, Maggiorani, Damien, Martini, Hélène, Douin‐Echinard, Victorine, Passos, Joao F., Lezoualc'h, Frank, Binda, Claudia, Parini, Angelo, Mialet‐Perez, Jeanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156293/
https://www.ncbi.nlm.nih.gov/pubmed/30003648
http://dx.doi.org/10.1111/acel.12811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156293/
https://www.ncbi.nlm.nih.gov/pubmed/30003648
http://dx.doi.org/10.1111/acel.12811

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