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Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation

Nitric Oxide (NO) is an intracellular signalling mediator, which affects many biological processes via the posttranslational modification of proteins through S-nitrosation. The availability of NO and NOS-derived reactive oxygen species (ROS) from enzymatic uncoupling are determined by the NO synthas...

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Detalles Bibliográficos
Autores principales: Bailey, Jade, Davis, Simon, Shaw, Andrew, Diotallevi, Marina, Fischer, Roman, Benson, Matthew A., Zhu, Hanneng, Brown, James, Bhattacharya, Shoumo, Kessler, Benedikt M., Channon, Keith M., Crabtree, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156325/
https://www.ncbi.nlm.nih.gov/pubmed/30254268
http://dx.doi.org/10.1038/s41598-018-32481-4