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Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation
Nitric Oxide (NO) is an intracellular signalling mediator, which affects many biological processes via the posttranslational modification of proteins through S-nitrosation. The availability of NO and NOS-derived reactive oxygen species (ROS) from enzymatic uncoupling are determined by the NO synthas...
Autores principales: | Bailey, Jade, Davis, Simon, Shaw, Andrew, Diotallevi, Marina, Fischer, Roman, Benson, Matthew A., Zhu, Hanneng, Brown, James, Bhattacharya, Shoumo, Kessler, Benedikt M., Channon, Keith M., Crabtree, Mark J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156325/ https://www.ncbi.nlm.nih.gov/pubmed/30254268 http://dx.doi.org/10.1038/s41598-018-32481-4 |
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