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Using both qualitative and quantitative data in parameter identification for systems biology models

In systems biology, qualitative data are often generated, but rarely used to parameterize models. We demonstrate an approach in which qualitative and quantitative data can be combined for parameter identification. In this approach, qualitative data are converted into inequality constraints imposed o...

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Detalles Bibliográficos
Autores principales: Mitra, Eshan D., Dias, Raquel, Posner, Richard G., Hlavacek, William S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156341/
https://www.ncbi.nlm.nih.gov/pubmed/30254246
http://dx.doi.org/10.1038/s41467-018-06439-z