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Using both qualitative and quantitative data in parameter identification for systems biology models
In systems biology, qualitative data are often generated, but rarely used to parameterize models. We demonstrate an approach in which qualitative and quantitative data can be combined for parameter identification. In this approach, qualitative data are converted into inequality constraints imposed o...
Autores principales: | Mitra, Eshan D., Dias, Raquel, Posner, Richard G., Hlavacek, William S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156341/ https://www.ncbi.nlm.nih.gov/pubmed/30254246 http://dx.doi.org/10.1038/s41467-018-06439-z |
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