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Long non‐coding RNA SNHG14 induces trastuzumab resistance of breast cancer via regulating PABPC1 expression through H3K27 acetylation

Currently, resistance to trastuzumab, a human epidermal growth factor receptor 2 (HER2) inhibitor, has become one major obstacle for improving the clinical outcome of patients with advanced HER2(+) breast cancer. While cell behaviour can be modulated by long non‐coding RNAs (lncRNAs), the contributi...

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Detalles Bibliográficos
Autores principales: Dong, Huaying, Wang, Wei, Mo, Shaowei, Liu, Qiang, Chen, Xin, Chen, Ru, Zhang, Yu, Zou, Kejian, Ye, Mulin, He, Xionghui, Zhang, Fan, Han, Jing, Hu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156344/
https://www.ncbi.nlm.nih.gov/pubmed/30063126
http://dx.doi.org/10.1111/jcmm.13758