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Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx‐001

The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx‐001, (1‐bromoacetyl‐3,3‐dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA‐NONOate), which spontaneously releases nitric oxide in aq...

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Detalles Bibliográficos
Autores principales: Oronsky, Bryan, Oronsky, Neil, Cabrales, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156345/
https://www.ncbi.nlm.nih.gov/pubmed/30010241
http://dx.doi.org/10.1111/jcmm.13791