An Effective Way of Producing Fully Assembled Antibody in Transgenic Tobacco Plants by Linking Heavy and Light Chains via a Self-Cleaving 2A Peptide

Therapeutic monoclonal antibodies (mAbs) have evolved into an important class of effective medicine in treatment of various diseases. Since the antibody molecule consists of two identical heavy chains (HC) and two light chains (LC), each chain encoded by two different genes, their expressions at sim...

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Detalles Bibliográficos
Autores principales: Lin, Yuan, Hung, Chiu-Yueh, Bhattacharya, Chayanika, Nichols, Starr, Rahimuddin, Hafsa, Kittur, Farooqahmed S., Leung, TinChung, Xie, Jiahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156355/
https://www.ncbi.nlm.nih.gov/pubmed/30283486
http://dx.doi.org/10.3389/fpls.2018.01379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156355/
https://www.ncbi.nlm.nih.gov/pubmed/30283486
http://dx.doi.org/10.3389/fpls.2018.01379

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