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KRAS RENAISSANCE(S) in Tumor Infiltrating B Cells in Pancreatic Cancer

KRAS is a driver mutation for malignant transformation. It is found in 30% of all cancers and in 90% of pancreatic cancers. The identification of small molecules selectively inhibiting KRAS mutants has been challenging, yet mutant KRAS has recently been shown to be targeted by tumor-infiltrating lym...

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Detalles Bibliográficos
Autores principales: Meng, Qingda, Valentini, Davide, Rao, Martin, Maeurer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156365/
https://www.ncbi.nlm.nih.gov/pubmed/30283732
http://dx.doi.org/10.3389/fonc.2018.00384