Tumor-Intrinsic PD-L1 Signaling in Cancer Initiation, Development and Treatment: Beyond Immune Evasion

Although the role of PD-L1 in suppressing the anti-tumor immune response is extensively documented, recent discoveries indicate a distinct tumor-intrinsic role for PD-L1 in modulating epithelial-to-mesenchymal transition (EMT), cancer stem cell (CSC)-like phenotype, metastasis and resistance to ther...

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Detalles Bibliográficos
Autores principales: Dong, Peixin, Xiong, Ying, Yue, Junming, Hanley, Sharon J. B., Watari, Hidemichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156376/
https://www.ncbi.nlm.nih.gov/pubmed/30283733
http://dx.doi.org/10.3389/fonc.2018.00386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156376/
https://www.ncbi.nlm.nih.gov/pubmed/30283733
http://dx.doi.org/10.3389/fonc.2018.00386

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