Parthenolide and DMAPT induce cell death in primitive CML cells through reactive oxygen species

Tyrosine kinase inhibitors (TKI) have become a first‐line treatment for chronic myeloid leuakemia (CML). TKIs efficiently target bulk CML cells; however, they are unable to eliminate the leukaemic stem cell (LSC) population that causes resistance and relapse in CML patients. In this study, we assess...

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Detalles Bibliográficos
Autores principales: Flores‐Lopez, Gabriela, Moreno‐Lorenzana, Dafne, Ayala‐Sanchez, Manuel, Aviles‐Vazquez, Socrates, Torres‐Martinez, Hector, Crooks, Peter A., Guzman, Monica L., Mayani, Hector, Chávez‐González, Antonieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156390/
https://www.ncbi.nlm.nih.gov/pubmed/30079458
http://dx.doi.org/10.1111/jcmm.13755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156390/
https://www.ncbi.nlm.nih.gov/pubmed/30079458
http://dx.doi.org/10.1111/jcmm.13755

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