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Peptidylarginine deiminase 4 concentration, but not PADI4 polymorphisms, is associated with ICU mortality in septic shock patients

The objective of our study was to evaluate the association between peptidylarginine deiminase 4 (PAD4) concentration and its polymorphisms with mortality in patients with septic shock. We prospectively evaluated 175 patients aged over 18 years with septic shock upon intensive care unit (ICU) admissi...

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Detalles Bibliográficos
Autores principales: Costa, Nara Aline, Gut, Ana Lúcia, Azevedo, Paula Schmidt, Polegato, Bertha Furlan, Magalhães, Eloá Siqueira, Ishikawa, Larissa Lumi Watanabe, Bruder, Rita de Cassia Siqueira, da Silva, Evelyn Aparecida, Gonçalves, Renan Braga, Tanni, Suzana Erico, Rogero, Marcelo Macedo, Norde, Marina Maintinguer, Cunha, Natália Baraldi, Zornoff, Leonardo Antonio Mamede, de Paiva, Sergio Alberto Rupp, Minicucci, Marcos Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156447/
https://www.ncbi.nlm.nih.gov/pubmed/30044533
http://dx.doi.org/10.1111/jcmm.13717