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Molecular Details of Retinal Guanylyl Cyclase 1/GCAP-2 Interaction

The rod outer segment guanylyl cyclase 1 (ROS-GC1) is an essential component of photo-transduction in the retina. In the light-induced signal cascade, membrane-bound ROS-GC1 restores cGMP levels in the dark in a calcium-dependent manner. With decreasing calcium concentration in the intracellular com...

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Detalles Bibliográficos
Autores principales: Rehkamp, Anne, Tänzler, Dirk, Iacobucci, Claudio, Golbik, Ralph P., Ihling, Christian H., Sinz, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156451/
https://www.ncbi.nlm.nih.gov/pubmed/30283299
http://dx.doi.org/10.3389/fnmol.2018.00330