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Ablation of Ggnbp2 impairs meiotic DNA double‐strand break repair during spermatogenesis in mice

Gametogenetin (GGN) binding protein 2 (GGNBP2) is a zinc finger protein expressed abundantly in spermatocytes and spermatids. We previously discovered that Ggnbp2 resection caused metamorphotic defects during spermatid differentiation and resulted in an absence of mature spermatozoa in mice. However...

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Detalles Bibliográficos
Autores principales: Guo, Kaimin, He, Yan, Liu, Lingyun, Liang, Zuowen, Li, Xian, Cai, Lu, Lan, Zi‐Jian, Zhou, Junmei, Wang, Hongliang, Lei, Zhenmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156456/
https://www.ncbi.nlm.nih.gov/pubmed/30055035
http://dx.doi.org/10.1111/jcmm.13751