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Tectorigenin inhibits RANKL‐induced osteoclastogenesis via suppression of NF‐κB signalling and decreases bone loss in ovariectomized C57BL/6

Metabolism of bone is regulated by the balance between osteoblast‐mediated bone formation and osteoclast‐mediated bone resorption. Activation of osteoclasts could lead to osteoporosis. Thus, inhibiting the activity of osteoclasts becomes an available strategy for the treatment of osteoporosis. Tecto...

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Detalles Bibliográficos
Autores principales: Ma, Chiyuan, Xu, Kai, Meng, Jiahong, Ran, Jisheng, Adel Abdo Moqbel, Safwat, Liu, An, Yan, Shigui, Wu, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156464/
https://www.ncbi.nlm.nih.gov/pubmed/30063119
http://dx.doi.org/10.1111/jcmm.13801