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Simulation and Stability Assessment of Anti-EpCAM Immunotoxin for Cancer Therapy
Purpose: Epithelial cell adhesion molecule (EpCAM) is a dominant antigen in human colon carcinoma tissue. Topology features of this antigen are different in normal and malignant conditions; for instance, EpCAM is much less accessible to antibodies in normal cells than in cancerous tissues. Hence, Ep...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156485/ https://www.ncbi.nlm.nih.gov/pubmed/30276141 http://dx.doi.org/10.15171/apb.2018.052 |