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Simulation and Stability Assessment of Anti-EpCAM Immunotoxin for Cancer Therapy

Purpose: Epithelial cell adhesion molecule (EpCAM) is a dominant antigen in human colon carcinoma tissue. Topology features of this antigen are different in normal and malignant conditions; for instance, EpCAM is much less accessible to antibodies in normal cells than in cancerous tissues. Hence, Ep...

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Detalles Bibliográficos
Autores principales: Hosseinian, Seyed-Ali, Haddad-Mashadrizeh, Aliakbar, Dolatabadi, Samaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156485/
https://www.ncbi.nlm.nih.gov/pubmed/30276141
http://dx.doi.org/10.15171/apb.2018.052